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1991. Thymocyte expression of RAG-1 and RAG-2: termination by T cell receptor cross-linking. Science 253:778–81 91. Chien YH, Iwashima M, Kaplan KB, Elliott JF, Davis MM. 1987. A new Tcell receptor gene located within the alpha locus and expressed early in T-cell differentiation. Nature 327:677–82 92. Pardoll DM, Fowlkes BJ, Bluestone JA, Kruisbeek A, Maloy WL, Coligan JE, Schwartz RH. 1987. Differential expression of two distinct T-cell receptors during thymocyte development. Nature 326:79–81 93.

1991. B cell development regulated by gene rearrangement: arrest of maturation by membrane-bound D mu protein and selection of DH element reading frames. Cell 65:47–54 135. Tornberg UC, Bergqvist I, Haury M, Holmberg D. 1998. Regulation of B lymphocyte development by the truncated immunoglobulin heavy chain protein Dmu. J. Exp. Med. 187:703–9 136. O’Shea CC, Thornell AP, Rosewell IR, Hayes B, Owen MJ. 1997. Exit of the pre-TCR from the ER/cis-Golgi is necessary for signaling differentiation, pro- 137.

Constantinescu A, Schlissel MS. 1997. Changes in locus-specific V(D)J recombinase activity induced by immunoglobulin gene products during B cell development. J. Exp. Med. 185:609–20 74. Born W, Rathbun G, Tucker P, Marrack P, Kappler J. 1986. Synchronized rearrangement of T-cell gamma and beta chain genes in fetal thymocyte development. Science 234:479–82 75. Snodgrass HR, Kisielow P, Kiefer M, Steinmetz M, von Boehmer H. 1985. Ontogeny of the T-cell antigen receptor within the thymus. Nature 313:592–95 76.

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