By Annual Reviews
Read or Download Annual Review of Immunology Volume 11 1993 PDF
Similar immunology books
Advances in Immunology, a original and hugely revered booklet, provides present advancements in addition to complete reports in immunology. Articles deal with the wide variety of subject matters that include immunology, together with molecular and mobile activation mechanisms, phylogeny and molecular evolution, and medical modalities.
This completely revised and up to date new version presents extraordinary insurance of crucial facets of immunology. Assuming no earlier wisdom of the topic, the e-book provides step by step aspect on issues corresponding to antigens, allergy, autoimmunity, reproductive immunity and immunodeficiency.
This e-book includes contributions from the main widespread specialists during this box. within the first part the overall ideas of blend remedy are mentioned, from purpose and technique to merits of hazards in day-by-day perform. the second one part issues particular illnesses. it really is awesome that even if there's rather a lot event with combining DMARDS in RA, for a number of different autoimmune illnesses mixture treatment has no longer but been constructed.
The rapidity of clinical growth over the past few years promises the application of this new selection of cutting-edge stories at the immunology of getting older, that's the results of large collaboration of greater than sixty of the best thinkers and students within the box, in cooperation with a couple of junior colleagues.
Additional info for Annual Review of Immunology Volume 11 1993
A widespread but unstated assumption seems to have been that T cell clones probably are memorycells. However,the regulatory influences affecting T cell clones reviewed above also are consistent with such clones being effector cells which are descendants of naive T cells rather than of memoryT cells. Althougheffector cells derived from naive T cells appear to be short-lived in vivo, their short life span maybe the consequenceof degradation and disappearance of most antigens encountered in nature.
ImmuMed. 168:543-58 nol. 7:145-73 11. Gajewski,T. , Fitch, 2. Heinzel, F. , Holaday, F. Anti-proliferative effect of B. , Coffman,R. , Locksley,R. M. IFN-~,in immune regulation. II. IFN-~, 1989. Reciprocal expression of interinhibits the proliferation of murinebone feron y or interleukin 4 duringthe resmarrowcells stimulated with IL-3, ILolution or progressionof murineleish4, or granulocyte-macrophagecolonymaniasis. Evidence for. expansion of stimulating factor. J. 141: distinct helper T cell subsets.
The mechanismby which IL-10 affects macrophages is not certain, although it does inhibit production of IL-1, IL-6, and TNF-c~by activated macrophages (19). Also, IL-10 inhibits lymphokineproduction by TH1 cells only if metabolically active macrophagesare used for stimulation; although fixed cells are less effective in stimulating lymphokineproduction by Tn 1 clones, IL-10 has no effect if fixed antigen-pulsed macrophagesare used (18). B cells also can secrete IL-10 (20) as can peritoneal macrophages that have been stimulated with lipopolysaccharide (LPS) (19).
Annual Review of Immunology Volume 11 1993 by Annual Reviews